Expression of adenylate cyclase and phosphodiesterase in development of temperature‐sensitive mutants with impaired metabolism of cAMP in drosophila melanogaster
Abstract:The mode of the developmental expression of adenylate cyclase (AC) and phosphodiesterase (PDE) in D melanogaster indicates that PDE plays the major role in the maintenance of a certain level of cAMP in postembryonic development, while both enzymes function in concert in imago. The ts-mutants ts155 and ts622, characterized upon their isolation as having an increased cAMP content and normal PDE activity, manifest high levels of AC activity from the third day of imago life. The levels of PDE activity characterist… Show more
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