Expression and significance of Fractalkine/CX3CL1 in MPO-AAV-associated glomerulonephritis rats
Junxue Ma,
Junjie Wang,
Hongli Kang
et al.
Abstract:Objective
To investigate the expression and significance of Fractalkine (CX3CL1, FKN) in serum and renal tissue of myeloperoxidase and anti-neutrophil cytoplasmic antibody associated vasculitis (MPO-AAV) rats.
Methods
Thirty Wistar-Kyoto (WKY) rats were randomly divided into: Control group, MPO-AAV group (400 µg/kg MPO mixed with Freund’s complete adjuvant i.p), MPO-AAV + Anti-FKN group (400 µg/kg MPO mixed with Freund’s complete adjuvant i.p), ant… Show more
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