Abstract:CHIP (Carboxy terminus of Hsc70 Interacting Protein) is an E3 ubiquitin ligase that can
induce ubiquitination and degradation of several oncogenic proteins. The expression of
CHIP is frequently lower in human breast cancer than in normal breast tissue. However, the
expression and role of CHIP in the canine mammary gland tumor (CMGT) remain unclear. We
investigated the potential correlation between CHIP expression and mammary gland tumor
prognosis in female dogs. CHIP expression was measured in 54 dogs by immun… Show more
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