Expression and regulation of vascular endothelial growth factor and its receptors flt-1, KDR in normal human endometrium

Wang, H.; Chen, G.

doi:10.1016/j.fertnstert.2004.07.869

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The Role Of Vegf In the Reproductive System During Embryo1

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2021

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“…In accordance with the upregulation of VEGF, VEGFR-1 and VEGFR-2 are also upregulated in the glandular epithelium in the secretory phase [ 44 ]. sFlt-1, a soluble antagonist of VEGF and PlGF, is increased distinctively in the proliferative phase but decreased to almost 25% of its proliferative phase peak value in the endometrium during the luteal phase [ 45 ].…”

Section: The Role Of Vegf In the Reproductive System During Embryomentioning

confidence: 95%

Role of Vascular Endothelial Growth Factor (VEGF) in Human Embryo Implantation: Clinical Implications

Guo

et al. 2021

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Vascular endothelial growth factor (VEGF) is a well-known angiogenic factor that plays a critical role in various physiological and pathological processes. VEGF also contributes to the process of embryo implantation by enhancing embryo development, improving endometrial receptivity, and facilitating the interactions between the developing embryo and the endometrium. There is a correlation between the alteration of VEGF expression and reproductive failure, including recurrent implantation failure (RIF) and recurrent miscarriage (RM). In order to clarify the role of VEGF in embryo implantation, we reviewed recent literature concerning the expression and function of VEGF in the reproductive system around the time of embryo implantation and we provide a summary of the findings reported so far. We also explored the effects and the possible underlying mechanisms of action of VEGF in embryo implantation.

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Section: The Role Of Vegf In the Reproductive System During Embryomentioning

confidence: 95%

Role of Vascular Endothelial Growth Factor (VEGF) in Human Embryo Implantation: Clinical Implications

Guo

et al. 2021

Biomolecules

View full text Add to dashboard Cite

show abstract

Expression and regulation of vascular endothelial growth factor and its receptors flt-1, KDR in normal human endometrium

Cited by 1 publication

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Role of Vascular Endothelial Growth Factor (VEGF) in Human Embryo Implantation: Clinical Implications

Role of Vascular Endothelial Growth Factor (VEGF) in Human Embryo Implantation: Clinical Implications

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