“…and in contrast to LPS, are thought to be highly conserved. A large number of leptospiral OMPs have been characterized such as OmpL1 [15,16], LipL32 [17,18], LipL41 [19,20], LipL21 [7,21], Lig proteins [22], and Loa22 [23,24], etc., and evaluated the potential use of them in various immunodiagnostic assays either alone or in combination with other proteins. The OMPs play an important in maintaining the cell structure, and attachment to various extra cellular matrix (ECM) components, and are protective immunogens in animal models of the disease [25,26].…”