“…The radioactivity of [ 3 H]-TdR was measured using a LS6500 liquid scintillation counter (Beckman Coulter, Fullerton, CA). The results are described as the average of triplicate counts per minute [32] .…”
Section: Purification Of T Cells and B Cells From Mouse Spleensmentioning
C-K suppresses the progression of CIA through regulating TCR, CD28, CTLA-4 and PD-1 expression, thus inhibiting the abnormal activation and differentiation of T lymphocytes.
“…The radioactivity of [ 3 H]-TdR was measured using a LS6500 liquid scintillation counter (Beckman Coulter, Fullerton, CA). The results are described as the average of triplicate counts per minute [32] .…”
Section: Purification Of T Cells and B Cells From Mouse Spleensmentioning
C-K suppresses the progression of CIA through regulating TCR, CD28, CTLA-4 and PD-1 expression, thus inhibiting the abnormal activation and differentiation of T lymphocytes.
“…Another recently published paper revealed that paeoniflorin might suppress human FLS proliferation by inhibiting the expression of β-arrestin 2 and up-regulating cAMP-PKA signaling pathway [54]. Based on the above clues, we will explore the mechanism of paeoniflorin from the change of EP receptor and downstream signaling.…”
“…The results indicated that for patients with RA, significant changes in their lncRNA expression profile in PBMCs may be related to inflammation. These pathways are related to signaling pathways such as TGF, TNF, EBRr and cAMP, which have been widely confirmed to have an important role in the pathogenesis of RA (30)(31)(32).…”
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