Expression Analysis of Wound Healing Genes in Human Periapical Granulomas of Progressive and Stable Nature

Immunoexpression of Interleukin 17, Transforming Growth Factor β1, and Forkhead Box P3 in Periapical Granulomas, Radicular Cysts, and Residual Radicular Cysts

“…A similar expression of TGF-b1 in PGs and RCs has also been reported in previous studies (8,24,25). However, Fukada et al (26) reported the absence of differences, and Garlet et al (27) showed that TGF-b1 expression was significantly higher in the inactive PGs.…”

Assessment of Apical Expression of Alpha-2 Integrin, Heat Shock Protein, and Proinflammatory and Immunoregulatory Cytokines in Response to Endodontic Infection

“…This result suggests that the healing process is still in course 7 days after root canal instrumentation. Recently, it was shown that ITGA4 mRNA expression was significantly higher in inactive compared with active periapical granulomas (9). However, no data for ITGA2 were found in the literature.…”

“…This process is tightly regulated through cell-cell interactions and cell-matrix signaling and promoted by integrins, a variety of cytokines and growth factors, and cell mitosis and apoptosis (9).…”

Bioinformatics, Interaction Network Analysis, and Neural Networks to Characterize Gene Expression of Radicular Cyst and Periapical Granuloma

“…As in several diseases, ICAL has been related to many forms of controlling gene expression (4,5,(17)(18)(19). However, most of these studies focused on isolated genes or metabolic pathways.…”