2005
DOI: 10.1016/j.fsi.2004.10.003
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Expressed sequence tags analysis of Atlantic halibut (Hippoglossus hippoglossus) liver, kidney and spleen tissues following vaccination against Vibrio anguillarum and Aeromonas salmonicida

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Cited by 48 publications
(27 citation statements)
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“…In addition, the recently established Fugu rubripes and Tetradon nigroviridis fish genome databases contain most hemostatic and serpin genes. Although such genes have been identified in different fish species, including serpins such as ATIII from Atlantic halibut [39], A1AT, ATIII, C1 inhibitor from Japanese flounder [40], only a few of them have been characterized, for instance, factor VII, IX, X, prothrombin, ATIII and HCII from zebrafish [41], a SPI from carp [42] and ATIII from salmon [43]. In this study, we report a novel heparin cofactor II gene from rock bream, O. fasciatus.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, the recently established Fugu rubripes and Tetradon nigroviridis fish genome databases contain most hemostatic and serpin genes. Although such genes have been identified in different fish species, including serpins such as ATIII from Atlantic halibut [39], A1AT, ATIII, C1 inhibitor from Japanese flounder [40], only a few of them have been characterized, for instance, factor VII, IX, X, prothrombin, ATIII and HCII from zebrafish [41], a SPI from carp [42] and ATIII from salmon [43]. In this study, we report a novel heparin cofactor II gene from rock bream, O. fasciatus.…”
Section: Discussionmentioning
confidence: 99%
“…This gene is constitutively expressed in the organs involved in primary defense in rainbow trout, Oncorhynchus mykiss but its expression in hepatocytes was not affected by in vitro treatment of lipopolysaccharide [49]. In Atlantic halibut, H. hippoglossus, however, there was high frequency of expressed sequence tags (ESTs) representing apolipoprotein A-I in fish vaccinated with L. anguillarum and A. salmonicida [50]. Lange et al [51] suggest that this gene has a role in development and homeostasis in Atlantic cod as shown by in-situ hybridization studies and TUNEL staining.…”
Section: Discussionmentioning
confidence: 99%
“…Hepcidin is known as an antimicrobial peptide involved in the first line of defence against invading pathogens, and numerous teleost hepcidin sequences have been published, including from Atlantic cod [28][29][30][31][32][33][34]. Hepcidin also has a role as a key regulator in iron homeostasis [35].…”
Section: Immune Gene Expressionmentioning
confidence: 99%