“…In addition, the recently established Fugu rubripes and Tetradon nigroviridis fish genome databases contain most hemostatic and serpin genes. Although such genes have been identified in different fish species, including serpins such as ATIII from Atlantic halibut [39], A1AT, ATIII, C1 inhibitor from Japanese flounder [40], only a few of them have been characterized, for instance, factor VII, IX, X, prothrombin, ATIII and HCII from zebrafish [41], a SPI from carp [42] and ATIII from salmon [43]. In this study, we report a novel heparin cofactor II gene from rock bream, O. fasciatus.…”