Exposure to solar ultraviolet radiation and breast cancer risk

Li, Yilun; Ma, Li

doi:10.1097/md.0000000000023105

Cited by 6 publications

(3 citation statements)

References 45 publications

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“…In our study, females showed significantly higher compliance rates than males, which might be attributed to fear of developing breast or thyroid cancer, both of which radiation is a major risk factor, especially among females. [31] In a study conducted by Chou et al, it was found that female orthopedic surgeons had a statistically significant 2.9-fold higher prevalence of breast cancer compared to the general U.S. female population, and a prevalence that was 85% higher than the general U.S. female population. [10] As suggested in the literature, radiation exposure and screening times decreased with increasing level of experience, showing that less experienced surgeons receive higher radiation dose.…”

Section: Discussionmentioning

confidence: 97%

The compliance with radiation protection and knowledge about radiation exposure among the orthopedic operating room personnel in Saudi Arabia

Almalki

Alballa

et al. 2021

JMSR

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Objectives: There is a rapid advancement in surgical techniques requiring real-time visualization and intraoperative X-ray utilization, leading to a higher radiation exposure among operating room (OR) staff. Taking preventive measures and reducing the unnecessary radiation exposure for the patient and the OR staff is essential. The study aimed to assess the compliance with using radiation protection equipment, as well as assessing the level of knowledge about radiation exposure among the orthopedic OR staff. Methods: This is a cross-sectional study that was conducted in Saudi Arabia. A 19-Item questionnaire that was developed and validated by Jentzsch et al. was sent to the emails of all the registered members of the Saudi Orthopedic Association, orthopedic physicians, OR nurses, and radiology technicians were included in the study. A Correlation procedure was performed to determine the relationship between knowledge and compliance scores. Results: We recruited 242 orthopedic OR personnel, 110 (45.5%) showed good knowledge and 120 (49.5%) showed good compliance. Lead apron was the most commonly used equipment, lead goggles use was the least. Females, radiology technicians, and sports and/or arthroplasty surgeons showed better compliance scores. Conclusion: The study reveals inadequate knowledge and compliance among OR staff regarding radiation protection. Therefore, we recommend providing training programs to minimize radiation hazards.

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Section: Discussionmentioning

confidence: 97%

The compliance with radiation protection and knowledge about radiation exposure among the orthopedic operating room personnel in Saudi Arabia

Almalki

Alballa

et al. 2021

JMSR

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“…Several studies argued whether more exposure to ultraviolet ray would result in higher incidence of breast cancer. However, their conclusions were inconsistent (13,14). Therefore, the influence of ultraviolet radiation on the development of breast cancer was still unknown.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological characteristics and features of molecular subtypes of breast cancer at high altitudes

et al. 2023

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BackgroundBreast cancer is one of the major malignancies threatening women’s health worldwide. The incidence of breast cancer at high altitudes increased over the years. But few studies focused on the characteristics of clinicopathology and molecular subtypes among breast cancer at high altitudes, which are still unknown. Tibet, with an average altitude over 4000 meters, is a representative city at high altitudes, lying in the Qinghai-Tibetan Plateau in southwestern China. This study aimed to identify the clinicopathological characteristics and features of molecular subtypes among Tibetan women with breast cancer, and provide evidence for cancer prevention and personalized therapeutics in high-altitude regions.MethodsBetween May 2013 and March 2022, 104 Tibetan women from high-altitude regions (Tibetan-group) and 34 Han Chinese women from low-altitude regions (Han-group), consecutively diagnosed with breast cancer in the Hospital of Chengdu Office of People’s Government of Tibetan Autonomous Region, were included in the study. We retrospectively reviewed the clinical character, altitudes of residence, tumor size, lymph nodes metastasis, distant metastasis, pathological type, immunohistochemical index, and molecular subtype.ResultsIn the study, we calculated the patient delay, equal to the period from symptoms onset to hospital visits. The patient delay of Tibetan-group was 7.47 ± 11.53 months, which was significantly longer than that of Han-group, 7.22 ± 22.96 months (p<0.05). Body Mass Index (BMI) was significantly different (p<0.05). Tumors in Tibetan-group were significantly larger than those in Han-group, 4.13 ± 2.98cm and 2.51 ± 0.82cm in diameter, respectively (p<0.05). According to ordinal logistic regression analysis, exposure to high altitudes might result in more advanced T stage (OR=2.45 95%CI 1.10-5.44). 41.3% (43/104) of cases in Tibetan-group had lymph node positive disease, whereas the percentage was found in 38.26% (13/34) in Han-group(p<0.05). The distribution of molecular subtypes was quite significantly different between two groups (p<0.05), according to the comparison of constituent ratios.ConclusionOur study verified that breast cancer at high altitudes possessed its own unique clinicopathological characteristics and distinct features of molecular subtypes. It broadened the understanding of this heterogenous disease and also provided valuable evidence for cancer prevention and personalized therapeutics of breast cancer at high altitudes.

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“…4,6,7 Although nurses are knowledgeable regarding the risk of exposure to ADs, they often do not adhere to safe work practices. 2,8 However, the knowledge, perceptions, and behavior in other healthcare job categories at risk of exposure have yet to be determined. 9,10 Nieweg et al 11 found that although 80% of respondents indicated they were aware that patient excreta may contain drug residual, only 21% of the nurses wore a gown, 18% wore a mask, and 3% used goggles.…”

Section: Introductionmentioning

confidence: 99%

Nurses’ knowledge, perceptions, and behaviors regarding antineoplastic drugs: the mediating role of protective knowledge^†

Liu

Lü

et al. 2022

Frontiers of Nursing

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Objective To explore the relationships between Chinese nurses’ knowledge, perceptions, and attitudes and their behavior and actual implementation of safety measures when handling antineoplastic drugs (ADs) in their daily work. Methods This was a multisite study conducted in 8 public hospitals in China. A self-administered questionnaire was sent to participants querying the degree of contact with ADs. The hypothesized relations were explored using structural equation modelling via the bootstrap method. Mediation analysis was applied to explore the mediating role of protective knowledge regarding AD exposure on the associations among protective training, using warning labels, and using protective masks. Results A total of 305 nurses were enrolled. The average age of all participants was 30.2 (standard deviation [SD]: 6.2) years. Nurses who had received protective training for AD exposure were more likely to use labels for ADs after age, body mass index (BMI), length of service, marital status, education, and department were controlled as covariates. The bias-corrected bootstrap of 95% confidence interval (CI) indicated that protective knowledge significantly mediated (23.4%) the association between protective training and using labels (indirect effect = 0.202, 95% CI: 0.009, 0.495); the proportion of mediation was 23.4%. Protective knowledge significantly mediated the association between protective training and using protective masks (indirect effect = 0.157, 95% CI: 0.048, 0.325); the proportion of mediation was 27.2%. Conclusions The findings of this study have provided baseline information on the current state of Chinese nurses’ perceptions, knowledge, and preventive behaviors toward ADs as the crisis is happening. Training is also recommended to improve nurses’ perceptions of the risks associated with ADs.

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Exposure to solar ultraviolet radiation and breast cancer risk

Abstract: Supplemental Digital Content is available in the text

Cited by 6 publications

References 45 publications

The compliance with radiation protection and knowledge about radiation exposure among the orthopedic operating room personnel in Saudi Arabia

The compliance with radiation protection and knowledge about radiation exposure among the orthopedic operating room personnel in Saudi Arabia

Clinicopathological characteristics and features of molecular subtypes of breast cancer at high altitudes

Nurses’ knowledge, perceptions, and behaviors regarding antineoplastic drugs: the mediating role of protective knowledge^†

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Exposure to solar ultraviolet radiation and breast cancer risk

Abstract: Supplemental Digital Content is available in the text

Cited by 6 publications

References 45 publications

The compliance with radiation protection and knowledge about radiation exposure among the orthopedic operating room personnel in Saudi Arabia

The compliance with radiation protection and knowledge about radiation exposure among the orthopedic operating room personnel in Saudi Arabia

Clinicopathological characteristics and features of molecular subtypes of breast cancer at high altitudes

Nurses’ knowledge, perceptions, and behaviors regarding antineoplastic drugs: the mediating role of protective knowledge†

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Product

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Nurses’ knowledge, perceptions, and behaviors regarding antineoplastic drugs: the mediating role of protective knowledge^†