2019
DOI: 10.1007/s00420-019-01509-1
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Exposure to metal fumes and circulating miRNAs in Algerian welders

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Cited by 12 publications
(3 citation statements)
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“…The authors found that a high concentration of cotinine in urine (as a measure of maternal smoking) was associated with miR-223 in maternal and cord blood. Although there is a lack of literature data on the effect of smoking on the expression of circulating miRNAs, the existing evidence have so far shown that air pollutants [ 57 ], working conditions [ 58 , 59 ] and metal exposure [ 60 ] might affect the regulation of circulating miRNA.…”
Section: Discussionmentioning
confidence: 99%
“…The authors found that a high concentration of cotinine in urine (as a measure of maternal smoking) was associated with miR-223 in maternal and cord blood. Although there is a lack of literature data on the effect of smoking on the expression of circulating miRNAs, the existing evidence have so far shown that air pollutants [ 57 ], working conditions [ 58 , 59 ] and metal exposure [ 60 ] might affect the regulation of circulating miRNA.…”
Section: Discussionmentioning
confidence: 99%
“…It has become a significant public health concern with toxic effects in the skin, oral, digestive, hepatic, respiratory, and renal systems [219], capable of inducing carcinogenesis through both genetic and epigenetic mechanisms, as evaluated in mice [220] and human cells [221]. People highly exposed to Cr may have high concentrations in the urine associated with the expression of miR-21 and miR-155, promoting chronic kidney diseases [222]. In addition to urine, Cr has been detected in blood where it induces miR-142-3p, miR-19a-3p, and miR-19b-3p downregulation, and in contrast with upregulation of miR-941.…”
Section: Effects Of Epigenetic Toxicants In Phenotypic Transformationmentioning
confidence: 99%
“…A cross-sectional study of 30 male welders was conducted to understand the association between metal particles from welding fumes exposure and circulating miRNA concentrations [259]. The presence of certain metals, specifically chromium and nickel, within blood and urine samples were significantly associated with the downregulation of expression of miRNAs -21, -146a, and -155 (biomarkers of renal function injury).…”
Section: Non-coding Rnasmentioning
confidence: 99%