Exposure to Lead in Drinking Water Causes Cognitive Impairment via an Alzheimer’s Disease Gene-Dependent Mechanism in Adult Mice
Katharina Kohler,
Teresa Macheda,
Misty M. Hobbs
et al.
Abstract:Background: Exposure to lead (Pb) is a major public health problem that could occur through contaminated soil, air, food, or water, either during the course of everyday life, or while working in hazardous occupations. Although Pb has long been known as a neurodevelopmental toxicant in children, a recent and growing body of epidemiological research indicates that cumulative, low-level Pb exposure likely drives age-related neurologic dysfunction in adults. Environmental Pb exposure in adulthood has been linked t… Show more
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