Exposure to home and school environmental triggers and asthma morbidity in <scp>C</scp>hicago inner‐city children

Banda, Elizabeth; Persky, Victoria; Damitz, Maureen; Williams, R.; Turyk, Mary E.

doi:10.1111/pai.12162

Cited by 14 publications

(10 citation statements)

References 29 publications

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“…18 Exposure to these major allergens can result in an increased risk for allergen sensitization, recurrent wheezing 19 and increased ED visits and hosptilatizations. 20 In addition, low-income, inner-city children are more frequently exposed to second hand smoke (SHS) than non-poor children. 10, 21-23 Indoor SHS exposure, particularly maternal smoking, was associated with a 52% increased risk of wheeze and 20% increased risk of asthma at age 5-18 years, 24 and any home SHS exposure was associated with increased asthma symptoms.…”

Section: Introductionmentioning

confidence: 99%

Factors associated with high short-acting β2-agonist use in urban children with asthma

Butz

Ogborn

Mudd

et al. 2015

Annals of Allergy, Asthma & Immunology

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Section: Introductionmentioning

confidence: 99%

Factors associated with high short-acting β2-agonist use in urban children with asthma

Butz

Ogborn

Mudd

et al. 2015

Annals of Allergy, Asthma & Immunology

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“…Pertinent allergens have been identified in inner-city schools [54][55][56][57][58]. Further still, there have been observations suggesting that exposure to allergens at schools is associated with worse asthma morbidity [59]. However, relevant indoor exposures for asthma are not limited to allergens [39,60].…”

Section: Environmental Exposures In Inner-city Schools: the Second Homementioning

confidence: 98%

Inner-city asthma

Dutmer

McGraw²,

Liu³

2016

Current Opinion in Allergy &Amp; Clinical Immunology

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Challenging previously conceived exposure-disease relationships, recent literature has elucidated new avenues in the complex interplay between immunologically active exposures and their effects on inner-city asthma. These findings, and improved understanding of other relevant exposures, could steer the direction of primary (and secondary) disease prevention research. Moreover, careful identification of asthma characteristics has effectively established predictors of exacerbations, highlighting individuals for which additional therapies are warranted and for whom such treatments are most likely to be effective.

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“…In birth cohorts, environmental exposure can be measured to allow analysing complex gene–environment interaction. Most of the other studies have been focused on the influence of environmental factors , such as early feeding (breastfeeding vs cow's milk formula) , diet/nutrients , postnatal growth and obesity and exposure to allergens , tobacco smoking, pollution, farm vs urban environment and infectious load. Regarding the environmental exposure, many hypotheses have been proposed, most of them with contrasting results.…”

Section: Evolution Genes and The Environmentmentioning

confidence: 99%

Respiratory allergies in childhood: Recent advances and future challenges

Caminati

Đurić-Filipović

Arasi

et al. 2015

Pediatric Allergy Immunology

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The burden of allergic airway diseases still represents a major health problem in childhood. Despite many different options are currently available for the diagnostic work-up and management, the overall disease control in terms of impact on quality of life, morbidity and mortality, is not yet satisfactory. The extreme variability of individual risk factors and severity determinants may account for it. On the other side, the knowledge of the multifaceted allergy background could pave the way to primary prevention, early intervention and disease course modification. In fact, most of current research is focusing on the identification of biological and clinical predictive markers of allergy and asthma onset. This review aims at summarizing the latest achievements concerning the complex inter-relation between genetic predisposition and environmental factors, and their impact on prevention strategies and early identification of at risk subjects. An update on the diagnostic and monitoring tools as well as an insight into the newest treatments options is also provided.

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Exposure to home and school environmental triggers and asthma morbidity in Chicago inner‐city children

Abstract: Examining the relationship of specific environmental exposures with asthma exacerbations and hospitalizations across age group and in different indoor environments warrants further study.

Cited by 14 publications

References 29 publications

Factors associated with high short-acting β2-agonist use in urban children with asthma

Factors associated with high short-acting β2-agonist use in urban children with asthma

Inner-city asthma

Respiratory allergies in childhood: Recent advances and future challenges

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