Exposure to 4% SF<sub>6</sub> during multiple breath washout affects subsequent infant tidal breathing analysis

Andrade, Ediane De Queiroz; Bayfield, Katie J; Blaxland, Anneliese; Wong, Alexander; Belinelo, Patricia de Gouveia; Sly, Peter D.; Collison, Adam; Murphy, Vanessa E.; Gibson, Peter G.; Mattes, Joërg; Robinson, Paul D.

doi:10.1002/ppul.25820

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2023

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“…However, SF 6 is a more viscous gas with a higher molar mass, and it is unknown if this affects tidal breathing in infants. To better understand the effect of 4% SF 6 on infant tidal breathing patterns, Andrade et al 6 performed tidal breathing measurements in a cohort of 12 infants before and after SF 6 MBW. They found that multiple tidal breathing measurements (respiratory rate [RR], ratio of time to peak expiratory flow over total expiratory time, and mean tidal expiratory flow) were significantly different pre‐ and post‐MBW.…”

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confidence: 99%