Exposure-response relationship between K. brevis blooms and reporting of upper respiratory and neurotoxin-associated symptoms

Abdullah, Laila; Ferguson, Scott; Niedospial, Daniel; Patterson, D.; Oberlin, S.; Nkiliza, A.; Bartenfelder, G.; Hahn-Townsend, C.; Parks, M.; Crawford, Fiona; Reich, Andrew; Keegan, A.; Kirkpatrick, Barbara; Mullan, Michael

doi:10.1016/j.hal.2022.102286

Cited by 6 publications

(2 citation statements)

References 16 publications

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“…Linear dose–response relationships between estimated exposure to aerosolized K. brevis and both upper respiratory tract and neurological outcomes were also observed among southwest Florida residents (n = 258). 67 Counts and intensity of respiratory outcomes, namely cough and sneezes, were used to create a respiratory irritation index. This index generally coincided with the size and intensity of blooms, which in turn was measured by an index on bloom severity based on detailed spatiotemporal data on K. brevis cell counts.…”

Section: Human Health Effects and Mechanismsmentioning

confidence: 99%

Harmful algal bloom aerosols and human health

et al. 2023

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Section: Human Health Effects and Mechanismsmentioning

confidence: 99%

Harmful algal bloom aerosols and human health

et al. 2023

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“…Recovery is complete 24 to 48 hours after ingestion. Exposure to aerosols containing brevetoxins can be responsible for eye irritation, dry cough and asthma-like respiratory discomfort (Arnich et al, 2021;Abdullah et al, 2022). Brevetoxins were detected for the first time in France in mussels from the Diana lagoon in Corsica in 2018 (Guillou et al, 2002;Amzil et al, 2021).…”

Section: Neurotoxic Shellfish Poisoningmentioning

confidence: 99%

Human shellfish poisoning: Implementation of a national surveillance program in France

Sinno‐Tellier

Abadie²,

Guillotin³

et al. 2023

Front. Mar. Sci.

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Toxic algae and their toxins represent an emerging public health issue, particularly due to global warming. The toxicological mechanisms of neurotoxic phycotoxins and their human health effects have been widely described (paralytic, neurological, amnesic, and ciguateric toxins). Food poisoning by bivalve shellfish (mussels, oysters…) can cause serious or even fatal neurological disorders, as bivalves accumulate toxins by feeding on harmful algae. However, retrospective study of human shellfish poisoning highlighted the difficulties in identifying cases related to neurotoxic phycotoxins by gathering clinical and biological diagnostic confirmations on the one hand, as well as environmental contaminations on the other. To improve the collection of shellfish poisoning data, the French Agency for Food, Environmental and Occupational Health and Safety (ANSES), French Poison Control Centers (PCCs), the French Research Institute for Exploitation of the Sea (Ifremer) and the French Defense Procurement Agency (DGA) have developed a prospective surveillance of neurotoxins from algal origin that combines monitoring of poisoning cases (clinical monitoring), of harmful algae and their toxins in shellfish production areas (environmental monitoring), as well as of toxins levels in seafood leftovers and in biological samples from poisoned subjects. This original clinical and environmental monitoring will allow us to have a more complete view of phycotoxin human exposures that are underreported, and to implement measures to protect consumers.

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