Abstract:Background: Human Infection Studies (HIS) involve intentional infection of volunteers with a challenge agent or pathogen in controlled conditions with the aim of developing vaccines. Though sub-Saharan Africa carries the highest burden of vaccine-preventable diseases, the region is only now being primed to conduct HIS relevant to its population. Given the imminent introduction of HIS in Zambia, we sought to understand potential participants’ willingness to volunteer for such studies. Methods : We used a qualit… Show more
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