Exploring various novel diagnostic and therapeutic approaches in treating diabetic retinopathy

Sood, Ankita; Baishnab, Suman; Gautam, Isha; Choudhary, Priya; Lang, Damanpreet Kaur; Jaura, Ravinder Singh; Singh, Thakur Gurjeet

doi:10.1007/s10787-023-01143-x

Cited by 1 publication

(2 citation statements)

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“…These potential benefits are likely linked to the increased blood flow generated by these interventions. 30 Moreover, PBT boosts collagen synthesis, crucial for wound closure and tissue remodeling. Collagen is integral to connective tissues, offering structural support during healing.…”

Section: Discussionmentioning

confidence: 99%

“…These factors have the ability to stimulate cell proliferation and differentiation, ultimately leading to tissue formation. [27][28][29][30][31][32][33][34][35][36][37][38] Considering the positive effects of PBT and APG in the treatment of DFUs, as well as its synergistic effects and its methods, in this study, the effects of these methods on DFUs will be investigated.…”

Section: Introductionmentioning

confidence: 99%

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Unveiling Therapeutic Potential: A Systematic Review of Photobiomodulation Therapy and Biological Dressings for Diabetic Foot Ulcers

Karimpour,

Amirmotamed,

Rashno

et al. 2023

J Lasers Med Sci

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Introduction: Diabetes poses a global health challenge, giving rise to various complications, including diabetic foot ulcers (DFUs). DFUs, marked by ischemic ulcers susceptible to infection and amputation, underscore the urgency for innovative treatments. This study investigated the impact of photobiomodulation therapy (PBT) and autologous platelet gel (APG) on DFUs recovery. Methods: We systematically searched Web of Science, EMBASE, MEDLINE, Cochrane Library, Scopus, and Google Scholar (2015-2023) by using pertinent terms like "photobiomodulation therapy," "low level light therapy," and "platelet gel." After meticulous data extraction and review, 57 articles were chosen and categorized. Among these, three randomized controlled trials involving 186 participants were selected for APG analysis. Results: Findings demonstrate that APG application carries minimal risk and offers promising improvements in healing time, grade, pain reduction, and granulation tissue formation. Similarly, diverse PBT modalities involving distinct probes and wavelengths exhibit the potential to enhance tissue perfusion, expedite healing, and impede wound progression, reducing the need for invasive interventions. Conclusion: PBT and APG emerge as valuable tools to augment wound healing, mitigate inflammation, and avert amputation, representing compelling therapeutic options for DFUs.

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Section: Discussionmentioning

confidence: 99%