Exploring the therapeutic mechanisms of resveratrol for treating arecoline‐induced malignant transformation in oral epithelial cells: insights into hub targets
Zhen Sun,
Xiaopeng Guo,
Changya Li
et al.
Abstract:BACKGROUNDBetel nut chewing is a significant risk factor for oral cancer due to arecoline, its primary active component. Resveratrol, a non‐flavonoid polyphenol, possesses anti‐cancer properties. It has been shown to inhibit arecoline‐induced oral malignant cells in preliminary experiments but the underlying mechanism remains unclear. This research therefore aimed to explore the potential therapeutic targets of resveratrol in treating arecoline‐induced oral cancer.METHODSData mining identified common targets a… Show more
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