Exploring the Single-Molecule Transient Interactions with Nanopore Frequency Spectrum
Ying-Huan Fu,
Xinyi Li,
Linyue Ma
et al.
Abstract:Interactions at the single-molecule interface play vital roles in biology and nanotechnology. However, nanopore technology hardly describes the transient interaction kinetics of small molecules due to fast translocation events and weak ionic current fluctuations. Here, we employed an improved frequency spectrum method for analyzing the ion current fluctuations induced by small molecules entering the nanopore. This frequency spectrum analysis method allows for the analysis of transient current changes beyond th… Show more
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