Exploring the role of the WNT5A rs566926 polymorphism and its interactions in non-syndromic orofacial cleft: a multicenter study in Brazil
Lorraynne dos Santos LARA,
Ricardo D. COLETTA,
Renato Assis MACHADO
et al.
Abstract:Associations between the
WNT5A
rs566926 variant and non-syndromic orofacial cleft (NSOC) have been reported in different populations.
Objective
This study aimed to investigate the role of the rs566926 single nucleotide polymorphism (SNP) in
WNT5A
and its interactions with SNPs in
BMP4, FGFR1, GREM1, MMP2
, and
WNT3
in the occurrence of NSOC in a Brazilian population.
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