Exploring the role of brain-derived extracellular vesicles in viral infections: from pathological insights to biomarker potential
Larise Oberholster,
Renaud Du Pasquier,
Amandine Mathias
Abstract:Extracellular vesicles (EVs) are membrane-bound vesicles secreted by all cell types that play a central role in cell-to-cell communication. Since these vesicles serve as vehicles of cellular content (nucleic acids, proteins and lipids) with the potential to cross biological barriers, they represent a novel attractive window into an otherwise inaccessible organ, such as the brain. The composition of EVs is cell-type specific and mirrors the physiological condition of the cell-of-origin. Consequently, during vir… Show more
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