Exploring the prognostic analysis of autophagy and tumor microenvironment based on monocyte cells in lung cancer
Bo Tao,
Ziming Wang,
Dacheng Xie
et al.
Abstract:A deep understanding of the biological mechanisms of lung cancer offers more precise treatment options for patients. In our study, we integrated data from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) to investigate lung adenocarcinoma. Analyzing 538 lung cancer samples and 31 normal samples, we focused on 3076 autophagy-related genes. Using Seurat, dplyr, tidyverse, and ggplot2, we conducted single-cell data analysis, assessing the quality and performing Principal Component Analysis (PC… Show more
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