Exploring the Potential Pharmacological Effect of Thymoquinone in Ameliorating the Acquisition and Expression of Vincristine Induced Neuropathic Pain in Mice
Mehreen Arif,
Naeem Ur Rehman,
Hurmat Malik
et al.
Abstract:Background: Chemotherapy-induced neuropathy (CIPN) is the most severe consequence, causing both sensory and motor impairment with an incidence of between 19% and over 85%. Leukaemia, lymphoma, and sarcoma are just a few of the cancers that are treated using vincristine (VCR), a typical anticancer treatment used in chemotherapy. Peripheral neuropathy caused by vincristine is the primary impediment to the efficacy of ongoing anti-cancer treatment and continued use. Objectives: The current study's goal was to con… Show more
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