We study the influence of the baryon chemical potential µ B on the properties of the Quark-Gluon-Plasma (QGP) in and out-of equilibrium. The description of the QGP in equilibrium is based on the effective propagators and couplings from the Dynamical QuasiParticle Model (DQPM) that is matched to reproduce the equation-of-state of the partonic system above the deconfinement temperature T c from lattice QCD. We study the transport coefficients such as the ratio of shear viscosity η and bulk viscosity ζ over entropy density s, i.e., η/s and ζ/s in the (T, µ) plane and compare to other model results available at µ B = 0. The out-of equilibrium study of the QGP is performed within the Parton-Hadron-String Dynamics (PHSD) transport approach extended in the partonic sector by explicitly calculating the total and differential partonic scattering cross sections based on the DQPM and the evaluated at actual temperature T and baryon chemical potential µ B in each individual space-time cell where partonic scattering takes place. The traces of their µ B dependences are investigated in different observables for symmetric Au+Au and asymmetric Cu+Au collisions such as rapidity and m T -distributions and directed and elliptic flow coefficients v 1 , v 2 in the energy range 7.7 GeV ≤ √ s NN ≤ 200 GeV.Particles 2020, xx, 5 2 of 16 from early beginning-directly after the Big Bang-when the matter was in the QGP phase at very large temperature T and about zero baryon chemical potential µ B , to the later stages of the universe, where in the expansion phase stars and Galaxy have been formed. Here, the matter is at low temperature and large baryon chemical potential. Relativistic and ultra-relativistic heavy-ion collisions (HICs) nowadays offer the unique possibility to study some of these phases, in particular a QGP phase and its phase boundary to the hadronic one. Furthermore, the phase diagram of strongly interacting matter in the (T, µ B ) plane can also be explored in the astrophysical context at moderate temperatures and high µ B [1], i.e., in the dynamics of supernovae or-more recently-in the dynamics of neutron star merges. In order to reproduce the mini Big Bangs in laboratories, heavy-ion accelerators are built which allow for investigating the creation of the QGP under controlled conditions. Hadronic spectra and relative hadron abundances from these experiments reflect important aspects of the dynamics in the hot and dense zone formed in the early phase of the reaction and collective flows provide information on the transport properties of the medium generated on short time scales. Whereas heavy-ion reactions at Relativistic Heavy-Ion Collider (RHIC) and Large Hadron Collider (LHC) energies probe a partonic medium at small baryon chemical potential µ B , the current interest is in collisions at lower bombarding energies where the net baryon density is higher and µ B accordingly. Such conditions will be realized in future accelerators at the Facility for Antiproton and Ion Research (FAIR) in Darmstadt and the Nuclotron-based Io...