Exploring the oral microbiome: an updated multidisciplinary oral healthcare perspective

Abstract

The oral cavity is home to diverse microbial content, collectively called the oral microbiome. The latest technological advancements have unraveled the intricacies of the oral microbiome. It can be of great importance for oral health care givers to know the fundamentals and latest developments in the field of the oral microbiome, as oral dysbiosis is associated with many common diseases frequently seen and managed by them. These diseases include dental caries, periodontitis, mucosal diseases (such as oral leukoplakia, oral lichen planus, and systemic lupus erythematosus), oral cancers, and even co-infections related to the current COVID-19 pandemic. The emergence of new genomic and molecular biology methodologies has been pivotal for understanding the role of the human microbiome in health and disease. The current review compiles oral microbiome in health and disease with a multidisciplinary dental approach. The insight into the oral microbiome, which is provided dental specialty wise in the current article will initiate and guide researchers of various disciplines in developing microbiome-based therapeutic or prophylactic management strategies, managing public health challenges by microbiome-based boarder interventions and divert resources for preserving and achieving a balanced oral microbiome.

Caries, Dental Erosion and Cariogenic Foods: A Review of Current Scientific Literature

“…Going deeper into the oral cavity, according to recent studies, it is possible to find around 700 to 1000 species of commensal bacteria in the oral cavity that form our oral microbiota. This way, it is possible to find two states of this microbiota in an individual: the eubiotic state (eubiosis), considered a state of balance and health between the host and its microbiota; The other state is dysbiotic (dysbiosis), which is related to imbalance and diseases, so it is in the state of oral dysbiosis that a person acquires related pathologies, such as periodontitis, gingivitis, cancer, cavities, among others (CHOWDHRY et al, 2023;MADEIRA, 2020).…”

Antimicrobial efficacy of direct air gas soft jet plasma for the in vitro reduction of oral bacterial biofilms

“…This can be friend and foe too, and the possible interaction with the human body can be protective and pathogenic 1 . The disruption of normal microflora is known as dysbiosis, this can contribute to various oral diseases such as dental caries or periodontitis 2 . These oral diseases can be correlated to a dental biofilm.…”