Abstract:Ferroptosis and autophagy, parts of regulated cell death, are essential in osteoarthritis, however, their mechanisms in age-related osteoarthritis (OA) are unclear. This study aims to investigate age-related OA cartilage hub genes associated with ferroptosis and autophagy and predict interaction mechanisms. We used GEO2R to identify age-related differentially expressed genes (DEGs) in GSE66554. We intersected DEGs with data from Ferroptosis and Autophagy Database to obtain ferroptosis and autophagy DEGs. We pe… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.