Abstract:Objective. Sepsis is a life-threatening condition, and the mechanism of coagulation dysfunction in sepsis remains unknown. We aimed to investigate the mechanism of coagulation dysfunction in sepsis.Methods. Standard methods were used to establish the sepsis models and generate gene expression profiles. Bioinformatics analysis was carried out by GO and KEGG enrichment analysis, construction of PPIs and screening of seed genes. Finally, seed genes were used to rebuild the disease-related pathways.Results. Our ex… Show more
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