Exploring the Interplay between Calcium Oxalate Crystals and Renal Tubular Epithelial Cell Injury: Implications for the Formation and Prevention of Kidney Stones
Youquan Zhao,
Boyu Yang,
Xiaochuan Yang
et al.
Abstract:Kidney stones are a prevalent and clinically significant disease that affects millions of individuals worldwide, which have emerged as a significant global public health concern. The majority of kidney stones are composed of calcium oxalate (CaOx). The mechanisms of stone formation and development are unclear, involving a complex interplay of physical and biochemical processes. The injury of tubular epithelial cells (TECs) represents a pivotal event in the pathogenesis of this condition, as it initiates oxidat… Show more
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