Exploring the genetics of lithium response in bipolar disorders
Marisol Herrera-Rivero,
Mazda Adli,
Kazufumi Akiyama
et al.
Abstract:Background
Lithium (Li) remains the treatment of choice for bipolar disorders (BP). Its mood-stabilizing effects help reduce the long-term burden of mania, depression and suicide risk in patients with BP. It also has been shown to have beneficial effects on disease-associated conditions, including sleep and cardiovascular disorders. However, the individual responses to Li treatment vary within and between diagnostic subtypes of BP (e.g. BP-I and BP-II) according to the clinical presentation. Mo… Show more
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