Exploring the causal association between genetically determined circulating metabolome and hemorrhagic stroke
Yaolou Wang,
Yingjie Shen,
Qi Li
et al.
Abstract:BackgroundHemorrhagic stroke (HS), a leading cause of death and disability worldwide, has not been clarified in terms of the underlying biomolecular mechanisms of its development. Circulating metabolites have been closely associated with HS in recent years. Therefore, we explored the causal association between circulating metabolomes and HS using Mendelian randomization (MR) analysis and identified the molecular mechanisms of effects.MethodsWe assessed the causal relationship between circulating serum metaboli… Show more
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