Exploring the boundary between temperament and generalized anxiety disorder: A receiver operating characteristic analysis

Rettew, David C.; Doyle, Alicia; Kwan, Monica; Stanger, Catherine; Hudziak, James J.

doi:10.1016/j.janxdis.2006.02.002

Cited by 37 publications

(24 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Another interpretation of the F2 Â GAD interaction involves the considerable overlap between GAD and more stable temperamental or trait constructs such as neuroticism, harm avoidance, and trait anxiety [Anthony et al, 2002;Rettew et al, 2006]. Among offenders with psychopathic traits, research separating individuals who are high vs. low on trait anxiety has shown differences on laboratory measures of modulation of responses to emotional and neutral stimuli [Lorenz and Newman, 2002], passive avoidance learning, [Newman and Schmitt, 1998], and fear-potentiated startle response [Sutton et al, 2002], suggesting that anxiety levels differentiate distinct subtypes of criminal psychopaths .…”

Section: Discussionmentioning

confidence: 99%

Psychopathy and Axis I psychiatric disorders among criminal offenders: relationships to impulsive and proactive aggression

Swogger

Walsh

Houston

et al. 2009

Aggressive Behavior

View full text Add to dashboard Cite

Both psychopathology and aggression are heterogeneous constructs. Determining which forms of psychopathology relate to risk for different classes of aggressive behavior has implications for risk recognition and management. This study examined the relationships of impulsive aggression (IA) and proactive aggression (PA) to psychopathy and symptoms of several Diagnostic and Statistical Manual Axis I disorders in a sample of criminal offenders. Results replicated prior findings from community samples of a broad relationship between psychopathology and IA. PA was related only to psychopathy. An interaction was found whereby IA was associated with impulsive-antisocial traits of psychopathy only for individuals with moderate to high levels of generalized anxiety. Results indicate that assessing and treating several Axis I disorders in offenders may decrease risk for IA. Moreover, current findings raise the possibility that generalized anxiety is a key, modifiable component of the relationship between IA and impulsive-antisocial traits.

show abstract

Section: Discussionmentioning

confidence: 99%

Psychopathy and Axis I psychiatric disorders among criminal offenders: relationships to impulsive and proactive aggression

Swogger

Walsh

Houston

et al. 2009

Aggressive Behavior

View full text Add to dashboard Cite

show abstract

“…Consistent with these genetic data, measures of emotionality such as neuroticism have been found to predict comorbidity patterns in these disorders [e.g. Chambers et al, 2004], yet a significant number of individuals with elevations on these dispositional variables do not have GAD or MDD [e.g., Rettew et al, 2006]. Further, Kessler et al [2004] warned that these results should be interpreted with caution, because models in these studies assume that the joint effects of genes and environment are additive and, thus, ignore genetic influence on environment.…”

Section: Diathesis Overlapmentioning

confidence: 93%

Is generalized anxiety disorder an anxiety or mood disorder? Considering multiple factors as we ponder the fate of GAD

et al. 2008

View full text Add to dashboard Cite

Generalized anxiety disorder (GAD) and major depressive disorder (MDD) demonstrate a strong relationship to each other at both genotypic and phenotypic levels, and both demonstrate substantial loadings on a higher-order negative affectivity factor. On the basis of these findings, there have been a number of calls to reclassify GAD in the same category as MDD (the "distress disorders"). However, any consideration of the reclassification of GAD should also take into account a number of other factors not only related to GAD and MDD but also to the overlap of these disorders with other anxiety and mood disorders. First, GAD has established reliability and validity in its own right, and specific features (e.g., worry) may become obscured by attempts at reclassification. Second, examination of the nature of the overlap of GAD and MDD with each other and with other disorders suggests a more complex pattern of differences between these conditions than has been suggested (e.g., MDD has strong relationships with other anxiety disorders, and GAD may be more strongly related to fear than it may first appear). Third, although findings suggest that GAD and MDD may have overlapping heritable characteristics, other evidence suggests that the two disorders may be distinguished by both environmental factors and temporal presentations. Finally, although overlap between GAD and MDD is reflected in their relationships to negative affectivity, temporal relationships between these disorders may be demonstrated by functional changes in emotional responsivity.

show abstract

“…Other work indicates that children identified as behaviorally inhibited at 21 months are more likely to develop an anxiety disorder 5-10 years later (Biderman et al 1993;Hirshfeld et al 1992). In a study specific to GAD, Rettew et al (2006) found that the temperamental trait of harm avoidance was strongly associated with a GAD diagnosis in children and adults. In families, behaviorally inhibited children are more likely to have a parent with an anxiety disorder , and children of parents with panic disorder or depression have been shown to display higher levels of BI compared to children of nonanxious parents (Rosenbaum et al 2000).…”

Section: Temperamentmentioning

confidence: 95%

The Developmental Psychopathology of Worry

Kertz

Woodruff-Borden

2011

Clin Child Fam Psychol Rev

View full text Add to dashboard Cite

Although childhood generalized anxiety disorder is generally understudied, worry, the cardinal feature of GAD, appears to be relatively common in youth. Despite its prevalence, there are few conceptual models of the development of clinical worry in children. The current review provides a framework for integrating the developmental psychopathology perspective, models of worry in adults, and data available on worry in children. General risk factors for the development of worry are considered, as well as potential pathways including genetics, temperament, cognitive, emotional and parenting influences, as well as the influence of cognitive development. Based on this review, it appears unlikely that main effects models will be able to explain the development of GAD or clinical worry in children and that a broad, complex model incorporating a number of factors and their interactions will best describe etiological and maintaining factors. With this perspective in mind, a number of suggestions for future work are offered.

show abstract

Exploring the boundary between temperament and generalized anxiety disorder: A receiver operating characteristic analysis

Cited by 37 publications

References 36 publications

Psychopathy and Axis I psychiatric disorders among criminal offenders: relationships to impulsive and proactive aggression

Psychopathy and Axis I psychiatric disorders among criminal offenders: relationships to impulsive and proactive aggression

Is generalized anxiety disorder an anxiety or mood disorder? Considering multiple factors as we ponder the fate of GAD

The Developmental Psychopathology of Worry

Contact Info

Product

Resources

About