Exploring the biomedical potential of iron vanadate Nanoparticles: A comprehensive review

Javad Javid-Naderi, Mohammad; Valizadeh, Nasrin; Banimohamad-Shotorbani, Behnaz; Shahgolzari, Mehdi; Shayegh, Fahimeh; Maleki-baladi, Reza; Sargazi, Saman; Fathi-karkan, Sonia

doi:10.1016/j.inoche.2023.111423

Cited by 9 publications

(2 citation statements)

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“…Additionally, understanding the death pathways of tumors at the cellular level can help develop promising therapeutic approaches [ 24 ]. Meanwhile, the application of nanomaterials to explore cancer therapeutic drugs has also been a research hotspot in recent years [ 25 – 27 ].…”

Section: Discussionmentioning

confidence: 99%

Research on lncRNA CTBP1-DT as a potential therapeutic target to regulate cell function in colorectal cancer

Fan,

Xu,

Kuang

2024

Discov Onc

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Background Colorectal cancer, which originates from the human colon or rectum, is one of the leading causes of death worldwide. Timely diagnosis and interventional therapy can significantly improve the prognostic survival of colorectal cancer patients, making regular screening and early detection essential. Aim To investigate the regulatory function of lncRNA CTBP1-DT (CTBP1-DT) on colorectal cancer cells and to assess its diagnostic significance. Methods A total of 102 patients with colorectal cancer and 92 healthy individuals were selected. The levels of CTBP1-DT and microRNA-30a-5p (miR-30a-5p) in serum and cell samples of the above subjects were compared by RT-qPCR. The effects of CTBP1-DT and miR-30a-5p dysregulation on the biological functions of colorectal cancer cells were analyzed via CCK-8, flow cytometry and Transwell assays. In addition, the ability of CTBP1-DT and miR-30a-5p to early identify colorectal cancer patients was determined through ROC curve. Results Serum CTBP1-DT was elevated in patients with colorectal cancer, which was obviously higher than in healthy controls. The expression of serum miR-30a-5p was downregulated in colorectal cancer. Both CTBP1-DT and miR-30a-5p have the value of distinguishing colorectal cancer, and the combined diagnostic ability is higher. Knockdown of CTBP1-DT directly targeted miR-30a-5p to repress cell activity and metastatic ability, whereas deregulation of miR-30a-5p eliminated the above inhibitory effects. Conclusion Overexpression of CTBP1-DT has a certain application potential in the diagnosis of colorectal cancer and may be a therapeutic target for colorectal cancer.

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Section: Discussionmentioning

confidence: 99%

Research on lncRNA CTBP1-DT as a potential therapeutic target to regulate cell function in colorectal cancer

Fan,

Xu,

Kuang

2024

Discov Onc

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“…3 The optical properties of rare earth orthovanadates are advantageous for optoelectronic applications such as sensors, solar panels, and light-emitting diodes. 4,5 In addition, they have magnetic properties that can be utilized for magnetic sensing and data storage. Orthovanadates of rare earth have been utilized as exceptional photocatalysts and water splitters.…”

Section: Introductionmentioning

confidence: 99%