Exploring CD26−/lo subpopulations of lymphocytes in asthma phenotype and severity: A novel CD4+ T cell subset expressing archetypical granulocyte proteins
Sara Vázquez‐Mera,
Laura Martelo‐Vidal,
Pablo Miguéns‐Suárez
et al.
Abstract:BackgroundAsthma pathology may induce changes in naïve/memory lymphocyte proportions assessable through the evaluation of surface CD26 (dipeptidyl peptidase 4/DPP4) levels. Our aim was to investigate the association of asthma phenotype/severity with the relative frequency of CD26−/lo, CD26int and CD26hi subsets within different lymphocyte populations.MethodsThe proportion of CD26−/lo, CD26int and CD26hi subsets within CD4+ effector T cells (Teff), total CD4− lymphocytes, γδ‐T cells, NK cells and NKT cells was … Show more
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