Exploring risk factors of short-term readmission in heart failure patients: A cohort study

Abstract

BackgroundThe risk of all-cause mortality in patients with heart failure (HF) has been studied previously. Readmission risk of HF patients was rarely explored. Thus, we aimed to explore early warning factors that may influence short-term readmission of HF patients.MethodsThe data of this study came from an HF database in China. It was a retrospective single-center observational study that collected characteristic data on Chinese HF patients by integrating electronic medical records and follow-up outcome data. Eventually, 1,727 patients with HF were finally included in our study.ResultsIn our study, the proportion of HF patients with New York Heart Association (NYHA) class II, III, and IV HF were 17.20%, 52.69%, and 30.11%, respectively. The proportion of patients with readmission within 6 months and readmission within 3 months was 38.33% and 24.20%, respectively. Multivariate logistic regression showed that NYHA class (pIII = 0.028, pIV < 0.001), diabetes (p = 0.002), Cr (p = 0.003), and RDW-SD (p = 0.039) were risk factors for readmission within 6 months of HF patients. NYHA class (pIII = 0.038, pIV < 0.001), CCI (p = 0.033), Cr (p = 0.012), UA (p = 0.042), and Na (p = 0.026) were risk factors for readmission within 3 months of HF patients.ConclusionsOur study implied risk factors of short-term readmission risk in patients with HF, which may provide policy guidance for the prognosis of patients with HF.

Relationship between Anemia and Readmission among Older Patients in Rural Community Hospitals: A Retrospective Cohort Study

“…Age as a determinant of readmission remains a topic of debate. Existing literature presents varied conclusions-some suggest improved outcomes with age, others indicate the opposite, and some show no discernible relationship [25][26][27]. Our findings, based on the multivariate analysis, did not identify age as a significant factor for readmission.…”

“…Although our study did not delve into the specific reasons for these readmissions, previous research indicated links between early readmissions and conditions such as heart failure, stroke, and COPD [11]. Other determinants of early readmission include high CCI score, prolonged hospitalization, inadequate patient education upon discharge, and medical emergency team (MET) calls [25][26][27]. Interestingly, another Australian retrospective study discovered that factors such as malnutrition, weekday discharge, and Indigenous status increased the risk of early readmission [26].…”

Predischarge Peak Atrial Longitudinal Strain and Plasma N-terminal Pro-hormone Brain Natriuretic Peptide as a Predictor of Short-term Rehospitalization and Cardiovascular Mortality in Patients with Acute Heart Failure

“…identified DM, NYHA functional class, serum creatinine, and red cell distribution width (SD) as independent risk factors for heart failure readmission within 6 months. [ 28 ] The mechanisms linking DM to heart failure outcomes involve changes in myocardial structure and energy metabolism. LV concentric remodeling in diabetic myocardium correlates with impaired energy metabolism and reduced myocardial systolic strain.…”

Diabetes Mellitus and Heart Failure: Epidemiology, Pathophysiologic Mechanisms, and the Role of SGLT2 Inhibitors

“…It is particularly important to note that the co-presentation of DM in patients with HF may predispose them to a worse prognosis. DM was an independent predictor of short-term readmission in a study of 1727 Chinese patients with HF [ 19 ]. DM has been previously established as a severe risk factor for mortality in patients with HF [ 20 ].…”