Exploring potential synergistic effects between dietary adenosine and inosine monophosphate on growth performance and acute stress‐induced immune responses of hybrid striped bassMorone chrysops × Morone saxatilis

Abstract

Two experiments were carried out to evaluate the effects of dietary adenosine monophosphate (AMP) and inosine monophosphate (IMP) on growth performance and acute stress‐induced immune response of hybrid striped bass (HSB). Nine isonitrogenous and isolipidic diets were prepared including a basal diet and eight treatments consisting of singular or combined additions of 0.5% AMP and 0.5% IMP, and combinations of 0.25% AMP and 0.25% IMP from each of two suppliers, Sigma‐Aldrich and Chem‐Impex. The first experiment included two 9‐weeks feeding trials in which triplicate groups of HSB (~9.7 g) were fed the experimental diets. Dietary 0.5% IMP (C‐Impex) showed significantly higher stimulation index of B‐lymphocyte proliferation compared with other dietary treatments. However, no significant synergistic effects between AMP and IMP supplementation were observed in production performance. In a subsequent experiment, HSB (~59.3 g) were fed the diets described previously for 2 weeks and subjected to a standardized acute stress challenge. Fish fed some of the dietary nucleotide treatments had significant enhancement of innate immunity at 0.5 and 12 hr poststress challenge compared with those fed the basal diet. Dietary 0.5% AMP (Chem‐Impex) provided the best capability for enhancing innate immunity during poststress and resistance to stress‐induced immunosuppression.

Alternative proteins as fish meal substitution in diets for largemouth bass (Micropterus salmoides): a mini review

“…Overall, these results indicated that combination of two or more alternative protein could substitute more FM in LBM feed, and meet the fish nutritional requirement. In addition, functional additives, such as paraprobiotics, nucleotide and phytogenic extracts, have been widely used in fish aquatic feeds (de Cruz et al., 2020; Siciliano et al., 2021). In LMB diet, Xie et al .…”

Yeast-extracted nucleotides and nucleic acids as promising feed additives for European sea bass (Dicentrarchus labrax) juveniles

“…Six isonitrogenous (45.16% protein) and isolipidic (17.43% lipids) diets were formulated to contain 2 low different FM levels (20 and 10%) as control treatments. Then, nucleotides (NT) and nucleic acid (NA) were added at the same dosage of 500 mg kg feed -1 in accordance with recent recommendations on same and other fish species (De Cruz et al, 2020;El-Nokrashy et al, 2021;Magouz et al, 2021). Experimental diets were produced via extrusion (pellet size = 2.0 mm) by the Danish Technological Institute (Taastrup, Denmark).…”