ExploringPorphyromonas gingivalisPathogenesis and Antibody Pool Effect Using a Novel Mouse Reproductive Model
Xiaoju Shi,
Maria Xu
Abstract:This study introduces a novel animal model consisting of two phases. In phase I, Balb/c mice received three intraperitoneal injections of antibodies and two subcutaneous challenges withPorphyromonas gingivalis. The mice were divided into seven groups: G1, G2, and G3 received a single monoclonal antibody targeting the major outer membrane protein RagB ofP. gingivalisand infection; G4 was infected without antibody; G5 and G6 received a mixture of monoclonal antibodies and infection; and G7 served as the healthy … Show more
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