2017
DOI: 10.1128/cvi.00544-16
|View full text |Cite
|
Sign up to set email alerts
|

Exploring Human Antimicrobial Antibody Responses on a Single B Cell Level

Abstract: Analysis of monoclonal antibodies (MAbs) derived from single B cell cloning has been highly beneficial for antimicrobial immunotherapy, vaccine design, and advancing our understanding of pathogen-triggered effects on the human immunoglobulin repertoire. Sequencing of variable domains of single B cells, and characterization of binding and functional activities of MAbs derived from those sequences, provides in-depth insight not only into sites of susceptibility for antibodymediated neutralization or opsonization… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2017
2017
2022
2022

Publication Types

Select...
4
1

Relationship

0
5

Authors

Journals

citations
Cited by 5 publications
(2 citation statements)
references
References 35 publications
0
2
0
Order By: Relevance
“…The relevance of sex as a biological variable and rigor of experimental approaches were emphasized. Important reports on these and other trending topics were published in CVI (8)(9)(10)(11)(12)(13)(14). In this rapidly expanding scientific environment, CVI remained committed to disseminating discoveries and scientific knowledge with high scholarly and editorial standards, in line with those of other ASM journals and following the tradition and excellence of the society itself.…”
Section: A Springtime For CVImentioning
confidence: 89%
“…The relevance of sex as a biological variable and rigor of experimental approaches were emphasized. Important reports on these and other trending topics were published in CVI (8)(9)(10)(11)(12)(13)(14). In this rapidly expanding scientific environment, CVI remained committed to disseminating discoveries and scientific knowledge with high scholarly and editorial standards, in line with those of other ASM journals and following the tradition and excellence of the society itself.…”
Section: A Springtime For CVImentioning
confidence: 89%
“…Future investigations would substantially benefit from the rapidly evolving knowledge regarding HIV-1and Flu-specific B cells, as well as newly emerging techniques, such as the fluorescent antigen probe and highthroughput single-cell sequencing. 12…”
Section: Hbv-specific B Cells In Hbv Infectionmentioning
confidence: 99%