Exploring drug release performance of hollow‐structured CS/SA/POSS composite gel spheres employing hydrophilic polymerizable AS‐POSS as crosslinker
Yang Meng,
Mengke Shi,
Wenbo Feng
et al.
Abstract:This study prepares a series of hollow‐structured CS/SA/POSS composite gel spheres with a diameter of ~2.5 mm by using hydrophilic Janus‐type polyhedral oligomeric silsesquioxane (AS‐POSS) as a crosslinking agent in combination with sodium alginate and chitosan via electrostatic adsorption/free radical polymerization. As the content of POSS increases, the wall thickness of the gel spheres also increases from 20 to 30 μm, leading to a more compact and smooth wall structure in the polymerized CS/SA/POSS composit… Show more
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