Exploring disparities in incidence and mortality rates of breast and gynecologic cancers according to the Human Development Index in the Pan-American region

Martínez-Mesa, Jeovany; Werutsky, Gustavo; Michiels, Stefan; Filho, Carlos Alberto Sampaio; Dueñas‐González, Alfonso; Zarba, J. J.; Mano, Max Senna; Villarreal‐Garza, Cynthia; Gómez, Henry L.; Barrios, Carlos H.

doi:10.1016/j.puhe.2017.04.017

Cited by 10 publications

(17 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mortality from prostate cancer showed a statistically significant increase until 2010 (APC 6.82) and then it stabilized, reaching an ASR of 18.4 per 100,000 men in 2018 in our study. Lima et al, in a study on mortality from prostate cancer in Aracaju, also found an upward trend with a statistically significant APC of 2.1 and an average Breast cancer had the highest mortality ASR among our female population (13.8 in the last five years of the series), which is similar to the world media (13.0) and to trends observed in the Pan-American region 1,26 . In our study, the temporal trend continues rising throughout the series.…”

Section: Discussionsupporting

confidence: 78%

Temporal trend of cancer mortality in a Brazilian state with a medium Human Development Index (1980–2018)

Lima

Siqueira

Moura

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Emerging economy countries in epidemiological transition have been especially challenged in the fight against cancer. This was an ecological study that aimed to describe the temporal trend of cancer mortality in a Brazilian northeastern state with a medium Human Development Index using official Brazilian mortality data from 1980 to 2018. We calculated the mortality crude rate (CR) and age-standardized rate (ASR) based on official population counts and estimates. The Joinpoint Regression Program, National Cancer Institute, USA, was used to calculate time trends of cancer mortality. There were 34,214 deaths from cancer, excluding nonmelanoma skin cancer, in Sergipe. The overall cancer mortality ASR was 70.1 and 57.9 per 100,000 men and women, respectively. For the last five years, the leading causes of cancer deaths were prostate (21.3), trachea, bronchus and lung (11.7), stomach (6.5), oral cavity (5.4) and liver and intrahepatic bile ducts (5.1) in males and breast (13.8), trachea, bronchus and lung (6.6), cervix (6.4), colon/rectum (5.8) and central nervous system (3.6) in females. In addition, there was a significant reduction in deaths from ill-defined causes in the series. Our results show that although there has been an increase in cancer mortality rates associated with Western lifestyles, such as prostate, breast and colon/rectum, high rates of cancer related to poverty and infections, such as stomach and cervix, still persist in Sergipe.

show abstract

Section: Discussionsupporting

confidence: 78%

Temporal trend of cancer mortality in a Brazilian state with a medium Human Development Index (1980–2018)

Lima

Siqueira

Moura

et al. 2020

Sci Rep

View full text Add to dashboard Cite

show abstract

“…They have reported a non-significant correlation of 0.091 and -0.051 between age-specific mortality rate and HDI, respectively in the whole world countries and Asia (10,19). In another study in the Pan American region, Martinez-Mesa et al have reported a positive correlation of 0.44 between natural log age-standardized breast cancer mortality rate and HDI in 2012 (20). As one of the most comprehensive studies in this field, Sharma has examined the relationship between HDI and the burden of breast cancer in 2016.…”

Section: Discussionmentioning

confidence: 98%

A Study of Relationship Between Breast Cancer Mortality Rate and Human Development Index: Global Trend Analysis from 1990 to 2017

et al. 2020

View full text Add to dashboard Cite

Background: Female breast cancer is known as one of the top five cancers in terms of mortality. Regarding contradictory reports about the mortality trend of this cancer and its association with the socio-economic status of the world countries, we aimed at assessing the global trend of female breast cancer mortality rate and investigate the relationship between its mortality rate and development status. Methods: The breast cancer Age Standardized Mortality Rate (ASMR) per 100,000 and Human Development Index (HDI) for 179 world countries were extracted, respectively from the Global Burden of Disease (GBD) 2017 study and the United Nations Development Programme (UNDP) database, for the period 1990 to 2017. The marginal modeling methodology was employed to analyze the global trend of ASMR and examine the relationship between ASMR and HDI. Results: The results showed a slightly constant curve for the global trend of breast cancer ASMR from 1990 to 2017 (around 17 per 100,000). Moreover, it was indicated that the ASMR is strongly related to development status. While countries with higher levels of HDI have experienced a declining trend of breast cancer mortality rate, countries with lower HDI levels experienced an ascending trend at this period. Conclusions: In general, the findings showed that mortality due to breast cancer is still a major health problem in total world countries. Hence, more efforts should be made to screen the patients in the early stages of the disease and promote the level of care, especially in countries with lower levels of economic development.

show abstract

“…Radical pelvic surgery is critically important in the management of these cancers, but it comes with the risk of urological complications. Ureters can be injured during surgery, and lymph node dissection and extensive surgery can damage pelvic nerves, blood vessels, and pelvic floor muscles, resulting in low urinary tract dysfunction (13)(14)(15)(16)).…”

Section: Introductionmentioning

confidence: 99%

“…Radical hysterectomy and radiotherapy disrupt the anatomy of the pelvic floor and the local nerve supply to the pelvic floor muscles. Bladder and bowel symptoms are common among cancer survivors, and these may persist long after treatment and adversely affect quality of life (13,19,20).…”

Section: Introductionmentioning

confidence: 99%

“…Ovarian cancer survivors had a prevalence of stress urinary incontinence of 32%-42%, urge urinary incontinence 15%-39%, prolapse 17% and sexual dysfunction 62-75%. Data regarding pelvic floor disorders in ovarian cancer survivors are limited, probably because the majority of patients are diagnosed in advanced stages III/IV which are associated with 5year survival rates of only 20-35% (13,20).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Pelvic floor disorders in gynecological malignancies. An overlooked problem?

Bodean¹,

Marcu²,

Spinu³

et al. 2018

JMMS

View full text Add to dashboard Cite

Cervical, endometrial, ovarian, vulvar, and vaginal cancers affect women of a broad age spectrum. Many of these women are still sexually active when their cancer is diagnosed. Treatment options for gynecological malignancies, such as gynecological surgery, radiation, and chemotherapy, are proven risk factors for pelvic floor dysfunction. The prevalence of urinary incontinence, fecal incontinence, and sexual dysfunction before cancer treatment is still unclear. Hypotheses have been raised in the literature that these manifestations could represent early symptoms of pelvic cancers, but most remain overlooked even in cancer surviving patients. The primary focus of therapy is always cancer eradication, but as oncological and surgical treatment options become more successful, the number of cancer survivors increases. The quality of life of patients with gynecological cancers often remains an underrated subject. Pelvic floor disorders are not consistently reported by patients and are frequently overlooked by many clinicians. In this brief review we discuss the importance of pelvic floor dysfunction in patients with gynecological malignant tumors.

show abstract

Exploring disparities in incidence and mortality rates of breast and gynecologic cancers according to the Human Development Index in the Pan-American region

Cited by 10 publications

References 29 publications

Temporal trend of cancer mortality in a Brazilian state with a medium Human Development Index (1980–2018)

Temporal trend of cancer mortality in a Brazilian state with a medium Human Development Index (1980–2018)

A Study of Relationship Between Breast Cancer Mortality Rate and Human Development Index: Global Trend Analysis from 1990 to 2017

Pelvic floor disorders in gynecological malignancies. An overlooked problem?

Contact Info

Product

Resources

About