Exploratory immunogenicity outcomes of peanut oral immunotherapy: Findings from the PALISADE trial
Caroline Nilsson,
Andrea Vereda,
Magnus P. Borres
et al.
Abstract:BackgroundImmunoglobulin E (IgE) and immunoglobulin G4 (IgG4) to peanut and its components may influence the clinical reactivity to peanut. Allergen‐specific immunotherapy is known for modifying both IgE and IgG4. Peanut oral immunotherapy may influence these serological parameters.MethodsExploratory analyses of serological data from participants receiving peanut (Arachis hypogaea) allergen powder‐dnfp (PTAH) and placebo in the double‐blind, randomized, phase 3 PALISADE trial were conducted to evaluate potenti… Show more
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