Exploration the inherent mechanism of polymorphism and mechanochromism based on isomerism and AIE theory

Liu, Wenjing; Wang, Yongtao; Ge, Guixian; Ma, Lei

doi:10.1016/j.dyepig.2019.107663

Cited by 15 publications

(4 citation statements)

References 42 publications

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“…The absorption maxima decrease gradually and shift from 633 to 665 nm (Figure S6, Supporting Information ), owing to the formation of a different aggregated state. 29 …”

Section: Resultsmentioning

confidence: 99%

“… The absorption spectra of BPBT with diverse f w were also investigated during the AIE titration experiment. The absorption maxima decrease gradually and shift from 633 to 665 nm (Figure S6, Supporting Information), owing to the formation of a different aggregated state …”

Section: Resultsmentioning

confidence: 99%

“…The absorption maxima decrease gradually and shift from 633 to 665 nm (Figure S6, Supporting Information), owing to the formation of a different aggregated state. 29 For in vitro diagnosis, BPBT molecules were encapsulated into PS nanoparticles using an organic solvent swelling method (Scheme 1a). 30 Transmission electron microscopy (TEM) images in Figure 1a,b show the morphologies of PS nanoparticles and AIE 810 NP, respectively.…”

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confidence: 99%

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Early Detection of SARS-CoV-2 Seroconversion in Humans with Aggregation-Induced Near-Infrared Emission Nanoparticle-Labeled Lateral Flow Immunoassay

Ren²,

et al. 2021

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An outbreak of coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses great threats to human health and the international economy. To reduce large-scale infection and transmission risk of SARS-CoV-2, a simple, rapid, and sensitive serological diagnostic method is urgently needed. Herein, an aggregation-induced emission (AIE) nanoparticle (AIE810NP, λem = 810 nm)-labeled lateral flow immunoassay was designed for early detection of immunoglobulin M (IgM) and immunoglobulin G (IgG) against SARS-CoV-2 in clinical serum samples. Using a near-infrared (NIR) AIE nanoparticle as the fluorescent reporter (△λ = 145 nm), the autofluorescence from the nitrocellulose membrane and biosample and the excitation background noise were effectively eliminated. After optimization, the limit of detection of IgM and IgG is 0.236 and 0.125 μg mL–1, respectively, commensurate with that of the enzyme-linked immunosorbent assay (ELISA) (0.040 and 0.039 μg mL–1). The sensitivity of the proposed AIE810NP-based test strip for detecting IgM and IgG is 78 and 95% (172 serum samples), commensurate with that of ELISA (85 and 95%) and better than that of a commercial colloidal gold nanoparticle (AuNP)-based test strip (41 and 85%). Importantly, the time of detecting IgM or IgG with an AIE810NP-based test strip in sequential clinical samples is 1–7 days after symptom onset, which is significantly earlier than that with a AuNP-based test strip (8–15 days). Therefore, the NIR-emissive AIE nanoparticle-labeled lateral flow immunoassay holds great potential for early detection of IgM and IgG in a seroconversion window period.

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“…The absorption maxima decrease gradually and shift from 633 to 665 nm (Figure S6, Supporting Information ), owing to the formation of a different aggregated state. 29 …”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Early Detection of SARS-CoV-2 Seroconversion in Humans with Aggregation-Induced Near-Infrared Emission Nanoparticle-Labeled Lateral Flow Immunoassay

Ren²,

et al. 2021

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“…It is worth highlighting that a nearly 100 nm difference in emission wavelength pre- and post-grinding is relatively uncommon among materials with similar force-induced color change attributes. 19 To decipher the mechanism behind this force-induced color alteration, we conducted X-ray diffraction (XRD) studies (Fig. S20, ESI†).…”

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confidence: 99%

An ultra-sensitive ratiometric fluorescent thermometer based on monomer and excimer dual emission

Feng,

Wu,

Chen

et al. 2023

Chem. Commun.

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The abnormal solvatochromism, high-contrast mechanochromism and internal mechanism of two AIEE-active β-diketones

et al. 2020

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Exploration the inherent mechanism of polymorphism and mechanochromism based on isomerism and AIE theory

Cited by 15 publications

References 42 publications

Early Detection of SARS-CoV-2 Seroconversion in Humans with Aggregation-Induced Near-Infrared Emission Nanoparticle-Labeled Lateral Flow Immunoassay

Early Detection of SARS-CoV-2 Seroconversion in Humans with Aggregation-Induced Near-Infrared Emission Nanoparticle-Labeled Lateral Flow Immunoassay

An ultra-sensitive ratiometric fluorescent thermometer based on monomer and excimer dual emission

The abnormal solvatochromism, high-contrast mechanochromism and internal mechanism of two AIEE-active β-diketones

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