Abstract:Background: Cabozantinib was found to be effective as a second-line treatment after sorafenib in patients with advanced hepatocellular carcinoma (HCC) in phase 3 CELESTIAL trial. So far, as immunotherapy has substituted molecular target agents as the primary systemic therapy for advanced HCC, cabozantinib is extensively used in the latest real-world clinical practice in a greatly different position than that shown by the CELESTIAL trial. In the current analysis, we examined the safety and effectiveness of cabo… Show more
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