Exploration of an Appropriate Threshold Value of a Novel 18F-ALF-NOTA-PRGD2 Positron Emission Tomography/Computed Tomography to Contour Tumor Volume of Glioblastoma Multiforme

Zhang, H.; Liu, N.; Huang, Yong; Lu, Hong; Fu, Zheng; Li, W.; Chen, Z.; Liu, Y.; Yu, Qingxi; Wang, S.; Zhu, Shaobo; Yu, Jinming; Yuan, Shuanghu

doi:10.1016/j.ijrobp.2016.06.925

International Journal of Radiation Oncology*Biology*Physics

2016

DOI: 10.1016/j.ijrobp.2016.06.925

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Exploration of an Appropriate Threshold Value of a Novel 18F-ALF-NOTA-PRGD2 Positron Emission Tomography/Computed Tomography to Contour Tumor Volume of Glioblastoma Multiforme

H. Zhang

N. Liu

Yong Huang

et al.

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2024

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“…Dimeric PRGD2 has been adopted as a new PET tracer in the early detection and staging of various tumors, due to its higher affinity for integrin αvβ3 receptor, a key factor in tumor angiogenesis 8,9 . 18 F-AlF-NOTA-PRGD2 is a novel radiotracer with 1-step synthesis by our laboratory and shows a higher uptake in the different types of cancers 10–13 . In this study, 18 F-AlF-NOTA-PRGD2 PET/CT showed a more sensitive diagnostic detection of the primary UM due to high tumor-to-brain ratio compared with that of 18 F-FDG PET/CT.…”

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confidence: 55%

Comparison of 18F-AlF-NOTA-PRGD2 and 18F-FDG PET/CT Imaging in a Case of Primary Uveal Melanoma

Zhu,

Pan,

Zhang

et al. 2024

Clin Nucl Med

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Uveal melanoma is the most common intraocular malignancy in adults with a high rate of metastasis and mortality. This study presented the PET/CT imaging of 18F-AlF-NOTA-PRGD2 and 18F-FDG in a patient with primary uveal melanoma. In addition to fundus photograph and ophthalmic ultrasonography, both 18F-AlF-NOTA-PRGD2 and 18F-FDG PET/CT imaging showed increased radioactive uptake in the lesions within the scan area. The tumoral lesions presented significantly higher uptake of 18F-AlF-NOTA-PRGD2 compared with that of 18F-FDG.

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mentioning

confidence: 55%

Comparison of 18F-AlF-NOTA-PRGD2 and 18F-FDG PET/CT Imaging in a Case of Primary Uveal Melanoma

Zhu,

Pan,

Zhang

et al. 2024

Clin Nucl Med

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Exploration of an Appropriate Threshold Value of a Novel 18F-ALF-NOTA-PRGD2 Positron Emission Tomography/Computed Tomography to Contour Tumor Volume of Glioblastoma Multiforme

Cited by 1 publication

References 0 publications

Comparison of 18F-AlF-NOTA-PRGD2 and 18F-FDG PET/CT Imaging in a Case of Primary Uveal Melanoma

Comparison of 18F-AlF-NOTA-PRGD2 and 18F-FDG PET/CT Imaging in a Case of Primary Uveal Melanoma

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