Exploration of alive-and-ventilator free days as an outcome measure for clinical trials of Resuscitative interventions
Ari Moskowitz,
Xianhong Xie,
Michelle Ng Gong
et al.
Abstract:Background
Outcome selection is a critically important aspect of clinical trial design. Alive-and-ventilator free days is an outcome measure commonly used in critical care clinical trials, but has not been fully explored in resuscitation science.
Methods
A simulation study was performed to explore approaches to the definition and analysis of alive-and-ventilator free days in cardiac arrest populations. Data from an in-hospital cardiac arrest observational cohort and from the Pragmatic Airway Resuscitation Tr… Show more
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