Exploration and investigation of various solid forms of an anti-glaucoma drug – dichlorphenamide

Abstract

Diclofenamide (or dichlorphenamide (DCF)) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-disulfamoylbenzene class. It is used for the treatment of acute angle closure glaucoma. However, its weak...

Polymorphism, phase transition, and physicochemical property investigation of Ensifentrine

“…[1][2][3][4][5] Owing to the variations in molecular packing, polymorphs of active pharmaceutical ingredients (APIs) often have varying physicochemical characteristics. [6][7][8][9][10][11][12][13][14] During the process of finding and developing new drugs, it is crucial to plan ahead and choose the best form. Therefore, it is necessary to be aware of as many forms as possible in order to choose the best one.…”