Exploiting the Potential of OLED-Based Photo-Organic Sensors for Biotechnological Applications

Krujatz, Felix; Or, Hild; Fehse, Karsten; Jahnel, Matthias; Werner, Ansgar; Bley, Th.

doi:10.4172/2150-3494.1000134

Cited by 3 publications

(6 citation statements)

References 62 publications

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“…Organic light-emitting diodes (OLEDs) and organic photon detectors (OPDs) are the subject of significant research efforts and continuous improvements (see Table 5) due to their multiple applications and advantages compared to their inorganic counterparts (Krujatz et al 2016). Organic electronics introduced some unbeatable advantages, such as direct on-chip integration, easy emission and detection, and compatibility with flexible substrates.…”

Section: Organic Electronic-based Designsmentioning

confidence: 99%

“…), being available in a large bandwidth emission spectrum. However, the OLEDs possess lower efficiencies (around 80 lm/W) than inorganic LEDs (higher than 200 lm/W) (Krujatz et al 2016). For enhancing widespread OLED implementation, the PI-SCALE project (pi-scale.eu) aims to integrate existing European infrastructures into an "European flexible OLED pilot line", operating in an open access mode and serving customers with individual product designs, validation of upscaling concepts, and system-level flexible OLED integration.…”

Section: Organic Electronic-based Designsmentioning

confidence: 99%

“…For enhancing widespread OLED implementation, the PI-SCALE project (pi-scale.eu) aims to integrate existing European infrastructures into an "European flexible OLED pilot line", operating in an open access mode and serving customers with individual product designs, validation of upscaling concepts, and system-level flexible OLED integration. Comprehensive reviews of the latest achievements in OLEDs used for fluorescence sensing may be found in Williams et al (2014), Jeong et al (2015), Krujatz et al (2016) and Yersin (2018). In Jansen-van Vuuren et al (2016), recent achievements in the field of OPDs were described, while the last comprehensive review about the integration of fluorescence sensors using organic optoeletronics with microfluidics (see Fig.…”

Section: Organic Electronic-based Designsmentioning

confidence: 99%

See 2 more Smart Citations

Miniaturization of fluorescence sensing in optofluidic devices

Măriuța

Colin

Barrot-Lattes

et al. 2020

Microfluid Nanofluid

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Successful development of a micro-total-analysis system (µTAS, lab-on-a-chip) is strictly related to the degree of miniaturization, integration, autonomy, sensitivity, selectivity, and repeatability of its detector. Fluorescence sensing is an optical detection method used for a large variety of biological and chemical assays, and its full integration within lab-on-a-chip devices remains a challenge. Important achievements were reported during the last few years, including improvements of previously reported methodologies, as well as new integration strategies. However, a universal paradigm remains elusive. This review considers achievements in the field of fluorescence sensing miniaturization, starting from off-chip approaches, representing miniaturized versions of their lab counter-parts, continuing gradually with strategies that aim to fully integrate fluorescence detection on-chip, and reporting the results around integration strategies based on optical-fiber-based designs, optical layer integrated designs, CMOS-based fluorescence sensing, and organic electronics. Further successful development in this field would enable the implementation of sensing networks in specific environments that, when coupled to Internet-of-Things (IoT) and artificial intelligence (AI), could provide real-time data collection and, therefore, revolutionize fields like health, environmental, and industrial sensing.

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Section: Organic Electronic-based Designsmentioning

confidence: 99%

Section: Organic Electronic-based Designsmentioning

confidence: 99%

Section: Organic Electronic-based Designsmentioning

confidence: 99%

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Miniaturization of fluorescence sensing in optofluidic devices

Măriuța

Colin

Barrot-Lattes

et al. 2020

Microfluid Nanofluid

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“…OLEDs provide homogeneous emission from both microscopic and macroscopic areas, offer microsecond or better response times, and allow precise intensity control. While the main application of OLEDs at present is in displays of mobile phones and TVs, OLEDs have already been used successfully in portable and wearable sensors [26][27][28][29][30][31][32][33] and, more recently, in optogenetics to stimulate neurons [34,35] and control cell behavior [19,20] . However, compared to conventional LEDs based on inorganic III-V semiconductor materials, they provide lower brightness and more broadband emission which may be problematic for fluorescence imaging.…”

Section: Introductionmentioning

confidence: 99%

“…Due to the small Stokes shift of eGFP, this spectral de-coupling is particularly challenging. [27] Several strategies have been suggested to make inorganic LEDs [39] and OLEDs [30][31][32]40,41] compatible with the requirements for fluorescence imaging, including the use of microcavities, DBRs, polarizers, and layers of absorbing molecules. We decided to use DBRs for our work because they offer steep spectral cut-off, high rejection in their stop band and high transmission in their pass band.…”

Section: Introductionmentioning

confidence: 99%

Narrowband Organic Light‐Emitting Diodes for Fluorescence Microscopy and Calcium Imaging

et al. 2019

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Fluorescence imaging is an indispensable tool in biology, with applications ranging from single‐cell to whole‐animal studies and with live mapping of neuronal activity currently receiving particular attention. To enable fluorescence imaging at cellular scale in freely moving animals, miniaturized microscopes and lensless imagers are developed that can be implanted in a minimally invasive fashion; but the rigidity, size, and potential toxicity of the involved light sources remain a challenge. Here, narrowband organic light‐emitting diodes (OLEDs) are developed and used for fluorescence imaging of live cells and for mapping of neuronal activity in Drosophila melanogaster via genetically encoded Ca2+ indicators. In order to avoid spectral overlap with fluorescence from the sample, distributed Bragg reflectors are integrated onto the OLEDs to block their long‐wavelength emission tail, which enables an image contrast comparable to conventional, much bulkier mercury light sources. As OLEDs can be fabricated on mechanically flexible substrates and structured into arrays of cell‐sized pixels, this work opens a new pathway for the development of implantable light sources that enable functional imaging and sensing in freely moving animals.

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Review—Advancements and Perspectives of Organic LED: In Depth Analysis of Architectural Design, Characteristics Parameters, Fabrication Techniques, and Applications

Yadav

Mittal

Negi

2023

ECS J. Solid State Sci. Technol.

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This article presents a review on various aspect of organic light emitting diodes (OLEDs), such as their working, various categorization, impact of fabrication methodologies (organic vapor phase deposition, vacuum thermal evaporation, inkjet printing etc.) that are low-cost and their applications in serval domains like medical, sensor, display, lighting etc. Three categorizations of OLED are discussed with respect to circuit, architecture and color of emission. Different layers of multi-layered structures such as injection layer, transport layer, block layers are also reviewed and their impacts are analyzed and compared. Moreover, an experimental fabrication technique for flexible substrate is reviewed that highlights low-cost fabrication method. In this technique, dynamic viscosity and contact angle are measured using rotational viscometer and contact angle meter, respectively. The result illustrates sheet resistance and effective opening ratio of 3.8 ohms per square and 82.5%, correspondingly. Additionally, various performance parameters like luminescence, external quantum efficiency, and current efficiency are compared. The paper also incorporates recent advancement in organic thin film transistors along with some OTFT driven OLED devices.

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Exploiting the Potential of OLED-Based Photo-Organic Sensors for Biotechnological Applications

Cited by 3 publications

References 62 publications

Miniaturization of fluorescence sensing in optofluidic devices

Miniaturization of fluorescence sensing in optofluidic devices

Narrowband Organic Light‐Emitting Diodes for Fluorescence Microscopy and Calcium Imaging

Review—Advancements and Perspectives of Organic LED: In Depth Analysis of Architectural Design, Characteristics Parameters, Fabrication Techniques, and Applications

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