“…Flow chemistry offers benefits such as improved safety and control of reactions, access to a wider range of reaction conditions, easier scale-up, and potential savings in energy use and wastage ( Newman and Jensen, 2013 ). Early adopters of continuous flow chemistry within the supramolecular community used microfluidic chips to influence process outcome ( Whitesides, 2006 ; Zhang et al, 2012 ; Foster et al, 2015 ; Parker et al, 2015 ; Yu et al, 2015 ; Gong et al, 2016 ); significant progress in flow technology has since opened a wealth of new opportunities for the field ( Arnon et al, 2016 ; Fang et al, 2018 ; Cohen-Gerassi et al, 2020 ; Méndez-Ardoy et al, 2020 ; Khoeini et al, 2021 ; Puigmarti-Luis et al, 2021 ).…”