Explicit description of viral capsid subunit shapes by unfolding dihedrons
Ryuya Toyooka,
Seri Nishimoto,
Tomoya Tendo
et al.
Abstract:Viral capsid assembly and the design of capsid-based nanocontainers critically depend on understanding the shapes and interfaces of constituent protein subunits. However, a comprehensive framework for characterizing these features is still lacking. Here, we introduce a novel approach based on spherical tiling theory that explicitly describes the 2D shapes and interfaces of subunits in icosahedral capsids. Our method unfolds spherical dihedrons defined by icosahedral symmetry axes, enabling systematic character… Show more
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