Explant Culture of Ovarian Tissue

Ünal, Murat Serkant; Önder, Elif; Çil, Nazlı; Çoban, Hatice Şiyzen; Seçme, Mücahit; Yıldırım, Gül; Mete, Gülçin Abban

doi:10.5505/vtd.2022.90947

Cited by 1 publication

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“…The presence of capillary vessels in the tunica albuginea adjacent to the corpus luteum, along with the observation of primordial follicles, has raised suspicions regarding postnatal oogenesis. Therefore, a thorough examination of the morphological changes in the ovule, Graafian follicle, and corpus luteum is necessary [1,7,8]. The developing Graaf follicle changes its location towards the outer part of the ovarian cortex towards ovulation.…”

Section: Introductionmentioning

confidence: 99%

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Korpus luteum oluşumu sırasında meydana gelen yapısal değişiklikler

ÜNAL,

TAN,

SEÇME

2024

Pam Tıp Derg

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Our study aims to investigate whether the formation of new follicles occurs in this region after the restructuring of the surface epithelium and tunica albuginea in the corpus luteum. In addition, another goal is to show the structures that develop from other follicles and the histological changes they undergo. Images of the structures formed from the Graaf follicle and the reconstructed corpus luteum were taken on ovarian tissue sections obtained from 6 Wistar albino-type rats aged 12-14 months. When the corpus luteum reaches its highest volume, the number of fibroblast-like cells in the surface epithelium and tunica albuginea is initially low. Later, it was observed that fibroblast-like cells along with the surface epithelium and tunica albuginea proliferated rapidly and increased the number of cell layers. In addition, it was observed that primordial and primary follicles were formed between the surface epithelium of the corpus luteum and in the tunica albuginea layer. Looking at the ovary as a whole and examining the developmental processes of the structures may help us better understand the dynamics of this organ.

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Section: Introductionmentioning

confidence: 99%

“…At this time, the surface epithelium also differentiates towards the cuboidal epithelium. New capillary vessels are formed in the thickened tunica albuginea [1,7,8].…”

Section: Introductionmentioning

confidence: 99%