Expired Domestic Drug - Paracetamol - as Corrosion Inhibitor for Carbon Steel in Acid Media

Duca, Delia-Andrada; Dan, Mircea Laurențiu; Vaszilcsin, Nicolae

doi:10.1088/1757-899x/416/1/012043

Cited by 5 publications

(3 citation statements)

References 12 publications

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“…Duca et al [ 108 ] compared the IE s of expired Paracetamol for carbon steel in 1 M HCl and 0.5 M H 2 SO 4 solutions at the same drug concentrations (150 ppm). Using the rapid evaluation methods PDP and EIS, in the first solution, IE s of about 85% were obtained, and for the second solution, over 93%.…”

Section: Inhibitory Efficiency Of Expired Drugsmentioning

confidence: 99%

Efficiency of Expired Drugs Used as Corrosion Inhibitors: A Review

et al. 2023

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Corrosion inhibitors represent one of the most commonly used methods for significantly reducing the corrosion rate of metals and alloys. Adsorption inhibitors have a wide range of applications in cooling water systems, deicing solutions for aircrafts, airports and ways, etching and degreasing solutions, oil pipelines, paints and coatings and metal processing solutions. Adsorption corrosion inhibitors of metals and alloys are generally organic compounds that contain structures with heteroatoms (N, P, S, As, O) in their molecules, having lone pair electrons or π electrons in aromatic rings or multiple bonds. They enable relatively strong interactions between the metal atoms and organic molecules, resulting in a protective layer of organic molecules adsorbed at the metal–corrosive solution interface. Most molecules of active substances from drugs contain similar structures, which is why many drugs have been already tested as corrosion inhibitors. One of the major disadvantages of using drugs for this purpose is their particularly high price. To overcome this impediment, the possibility of using expired drugs as corrosion inhibitors has been investigated since 2009. The present paper is an exhaustive compilation of the scientific published papers devoted to the use of expired drugs as corrosion inhibitors in various aggressive solutions. The inhibitory efficiencies of expired drugs are presented as a function of the studied metal or alloy and the nature of the aggressive solution, as well as the concentration of the inhibitor in such a solution. Research has especially been focused on mild and carbon steel and less on stainless steel, as well as on some metals such as copper, zinc, nickel, tin and aluminum and its alloys. The experimental methods used to assess the inhibitory efficiencies of expired drugs are briefly discussed. Also, the available information on the stability of the active substances in the drugs is presented, although most authors were not concerned with this aspect. Finally, several actions are revealed that must be undertaken by researchers so that the results obtained in the study of the anticorrosive action of expired drugs can be applied at the industrial level and not remain only an academic concern.

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Section: Inhibitory Efficiency Of Expired Drugsmentioning

confidence: 99%

Efficiency of Expired Drugs Used as Corrosion Inhibitors: A Review

et al. 2023

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“…These findings suggest that expired medications can be safely repurposed for corrosion inhibition purposes. Their nontoxic attributes and minimal environmental impact position them as potential candidates to replace traditional toxic chemical corrosion inhibitors (13). Expired medications have even been recognized as part of the family of green corrosion inhibitors.…”

Section: Introductionmentioning

confidence: 99%

Studying the Effectiveness of an Expired Betamethasone Drug in Sulfuric Acid Solutions to Examine the Corrosive Behavior of Copper Using Weight Loss and Experimental Design

ATTAR,

BENCHADLI

2024

Journal of the Turkish Chemical Society Section A: Chemistry

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Utilizing expired pharmaceuticals as corrosion inhibitors for copper in acidic environments offers compelling advantages, including cost-effectiveness, reduced toxicity compared to traditional inhibitors, and contribution to pharmaceutical waste reduction through recycling. This study investigates the corrosion inhibition of copper in a sulfuric acid solution using varying concentrations of Expired Betamethasone Drug, employing weight loss and Experimental Design methods. The influence of temperature on copper's corrosion behavior is examined within the range of 293–333 K. Results show that inhibition efficiency increases with higher inhibitor concentrations but decreases with rising temperature. Thermodynamic analyses elucidate adsorption and activation processes, revealing that the adsorption of Expired Betamethasone Drug on copper surfaces is characterized as endothermic and spontaneous, aligning well with the Langmuir and Frumkin adsorption isotherms. The activation and free energies of inhibition reactions support a mechanism of physical adsorption. To establish the relationship between factors and responses, we employ response surface methodology (RSM) with regression statistical analysis and probabilistic assessment. Statistical analysis demonstrates highly significant quadratic models for inhibition efficiencies (IE) with a coefficient of multiple regressions (R²) of 0.999. Further model validation confirms a strong fit (adjusted R² = 0.997), with experimental observations closely matching predictions and a highly significant model (Q² = 0.989). The findings reveal that this expired drug exhibits substantial inhibitory power, exceeding 96%, in both experimental and predictive calculations.

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“…Ibuprofen, for example, has demonstrated efficacy in halting the deterioration of carbon steel in acidic environments [9]. Paracetamol (acetaminophen) is believed to prevent carbon steel corrosion in acidic environments by forming a protective layer on the metal surface through its interaction with metal ions [10]. This action is thought to occur as the drug adheres to the surface, establishing a barrier that prevents additional corrosion.…”

Section: Introduction *mentioning

confidence: 99%

Corrosion Inhibitors for Carbon Steel in HCl Environment: Synthesis and Characterization of Trimethoprim-Metal Complexes

NASER,

HAMMED,

ALSHEMARY

et al. 2024

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This study is about making and figuring out what trimethoprim (TM), a popular corrosion inhibitor, is like and then using it as an inhibiting agent to stop corrosion in carbon steel in acid media (HCl solution) through adsorption. TM has also been known as the prevalent anti-corrosive agent. It can be added to a liquid or gas to slow the pace of a chemical reaction (in the case of a material – typically a metal or alloy – that corrodes when it encounters the fluid). Many antibiotic compounds, such as TM derivatives, diiron salt dihydrate, and diiron salt tetrahydrate, have active groups that can stop metal from corroding. Spectroscopic methods like XRD (X-ray difraction), FTIR (Fourier transform infrared spectroscopy), UV-visible (ultraviolet-visible spectroscopy), and TGA (thermogravimetric analysis) were used to study the TM drug. Similarly, the OCP (open circuit voltage) technique was introduced to assess the corrosion resistance and the density of current vs. voltage. Finally, this study revealed that TM drugs could be suggested for introduction as corrosion inhibitors due to their simple production and the fact that they have many active groups that exhibit the ability to coordinate with carbon steel. Our study revealed that changes in inhibitor concentrations, the solution's acidity, and the metal's surface area all contribute to adsorption.

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Expired Domestic Drug - Paracetamol - as Corrosion Inhibitor for Carbon Steel in Acid Media

Cited by 5 publications

References 12 publications

Efficiency of Expired Drugs Used as Corrosion Inhibitors: A Review

Efficiency of Expired Drugs Used as Corrosion Inhibitors: A Review

Studying the Effectiveness of an Expired Betamethasone Drug in Sulfuric Acid Solutions to Examine the Corrosive Behavior of Copper Using Weight Loss and Experimental Design

Corrosion Inhibitors for Carbon Steel in HCl Environment: Synthesis and Characterization of Trimethoprim-Metal Complexes

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