1977
DOI: 10.2105/ajph.67.6.545
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Expired air carbon monoxide and serum thiocyanate as objective measures of cigarette exposure.

Abstract: Expired air carbon monoxide (CO) and serum thiocyanate (SCN) were used to assess exposure to cigarettes in 139 middle-aged men. Subjects who reported smoking cigarettes generally had CO levels exceeding 8ppm and SCN levels exceeding lOOumolIL; non-smokers had lower levels. For both tests the mean concentration among men smoking more than one pack daily was three times that of nonsmokers. There is a high correlation between the two tests (r = .571 for smokers), an association that was largely independent of the… Show more

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Cited by 212 publications
(66 citation statements)
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“…It is advised that, whenever possible, multiple biochemical measures such as CO and saliva thiocyanate be included in smoking research because they provide a more reliable assessment of subjects' smoking behavior and may enhance the accuracy of subjects' self-reported smoking. [20][21][22] While conclusions regarding the long-term effectiveness of the experimental program are premature, the post-test results are encouraging. Future research is presently underway to assess the long-term effectiveness of the program.…”
Section: Discussionmentioning
confidence: 99%
“…It is advised that, whenever possible, multiple biochemical measures such as CO and saliva thiocyanate be included in smoking research because they provide a more reliable assessment of subjects' smoking behavior and may enhance the accuracy of subjects' self-reported smoking. [20][21][22] While conclusions regarding the long-term effectiveness of the experimental program are premature, the post-test results are encouraging. Future research is presently underway to assess the long-term effectiveness of the program.…”
Section: Discussionmentioning
confidence: 99%
“…This is consistent with previous reports4,5 that sex differences are generally small at this age. Correlation coeffi-*93 White, 2 Black, 4 Hispanic or Oriental. There were no significant differences in BP by race.…”
Section: Descriptive Statisticsmentioning
confidence: 99%
“…28 It was one of the earliest biochemical method used in determining smoking status of the individuals. 29 Carbon monoxide levels, measured by breathe analyser, in expired air, showed 96% sensitivity and 100% specificity in determining the smoking status among smokers and nonsmokers. 30 It confirmed smoking cessation (quitters) in 74% of the past smokers.…”
Section: Expired Carbon Monoxide In Breathementioning
confidence: 96%
“…Salivary thiocyanate measurement in saliva was developed as an alternative to expired carbon monoxide measurement. 29 However, several limitations were found in measuring this analyte in biological fluids. The main limitation was the sensitivity and specificity of the assay, which was found to be lowered compared to expired carbon monoxide and other new methods.…”
Section: Salivary Thiocyanatementioning
confidence: 99%